Last updated: 2023-01-11

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Knit directory: Serreze-T1D_Workflow/

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    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-4_peak.marker-UNC8099452_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-4_peak.marker-UNC8161950_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-5_peak.marker-UNC9678100_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-5_peak.marker-UNC9678931_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-6_peak.marker-UNC12162881_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-6_peak.marker-backupUNC060363218_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-7_peak.marker-UNC12719038_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-7_peak.marker-UNCHS022024_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-8_peak.marker-UNC14948439_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-8_peak.marker-UNCHS023592_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-9_peak.marker-UNC16009822_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-9_peak.marker-UNC17271730_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-X_peak.marker-UNC31358512_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_blup_sub_chr-X_peak.marker-UNCHS049472_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-10_peak.marker-UNC18805053_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-10_peak.marker-UNCHS029427_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-11_peak.marker-UNCHS031753_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-11_peak.marker-UNCHS031802_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-12_peak.marker-JAX00326005_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-12_peak.marker-UNC21995304_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-13_peak.marker-JAX00370189_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-13_peak.marker-UNCHS035661_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-14_peak.marker-UNC24597582_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-14_peak.marker-UNCHS039096_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-15_peak.marker-UNC25489755_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-15_peak.marker-UNCHS040614_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-16_peak.marker-UNCHS042686_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-17_peak.marker-UNCHS043777_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-17_peak.marker-UNCHS043880_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-18_peak.marker-UNC29296831_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-18_peak.marker-UNC29297751_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-19_peak.marker-UNC30069852_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-19_peak.marker-UNC30386742_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-1_peak.marker-UNCHS001121_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-1_peak.marker-UNCHS002308_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-2_peak.marker-UNC3990359_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-2_peak.marker-UNCHS006135_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-3_peak.marker-JAX00105915_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-3_peak.marker-UNC6020011_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-4_peak.marker-UNC8099452_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-4_peak.marker-UNC8161950_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-5_peak.marker-UNC9678100_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-5_peak.marker-UNC9678931_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-6_peak.marker-UNC12162881_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-6_peak.marker-backupUNC060363218_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-7_peak.marker-UNC12719038_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-7_peak.marker-UNCHS022024_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-8_peak.marker-UNC14948439_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-8_peak.marker-UNCHS023592_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-9_peak.marker-UNC16009822_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-9_peak.marker-UNC17271730_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-X_peak.marker-UNC31358512_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_genes_chr-X_peak.marker-UNCHS049472_lod.drop-1.5_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_gm_qtl_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_marker.freq_low.geno.freq.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_marker.freq_low.geno.freq.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/ici-sick.vs.ici-eoi_marker.freq_low.geno.freq.removed_sample.outliers.removed_geno.ratiov_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_marker.freq_low.geno.freq.removed_sample.outliers.removed_geno.ratiov_4.batches_myo_mis.csv
    Untracked:  data/ici-sick.vs.ici-eoi_marker.freq_low.probs.freq.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_marker.freq_low.probs.freq.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/ici-sick.vs.ici-eoi_marker.freq_low.probs.freq.removed_sample.outliers.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/ici-sick.vs.ici-eoi_marker.freq_low.probs.freq.removed_sample.outliers.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/ici.vs.pbs_gm_qtl_snpsqc_dis_no-x_updated_4.batches_myo.csv
    Untracked:  data/ici.vs.pbs_marker.freq_low.geno.freq.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/ici.vs.pbs_marker.freq_low.geno.freq.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/ici.vs.pbs_marker.freq_low.geno.freq.removed_sample.outliers.removed_geno.ratiov_4.batches_myo.csv
    Untracked:  data/ici.vs.pbs_marker.freq_low.geno.freq.removed_sample.outliers.removed_geno.ratiov_4.batches_myo_mis.csv
    Untracked:  data/ici.vs.pbs_marker.freq_low.probs.freq.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/ici.vs.pbs_marker.freq_low.probs.freq.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/ici.vs.pbs_marker.freq_low.probs.freq.removed_sample.outliers.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/ici.vs.pbs_marker.freq_low.probs.freq.removed_sample.outliers.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/myo-yes.vs.myo-no_marker.freq_low.geno.freq.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/myo-yes.vs.myo-no_marker.freq_low.geno.freq.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/myo-yes.vs.myo-no_marker.freq_low.geno.freq.removed_sample.outliers.removed_geno.ratiov_4.batches_myo.csv
    Untracked:  data/myo-yes.vs.myo-no_marker.freq_low.geno.freq.removed_sample.outliers.removed_geno.ratiov_4.batches_myo_mis.csv
    Untracked:  data/myo-yes.vs.myo-no_marker.freq_low.probs.freq.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/myo-yes.vs.myo-no_marker.freq_low.probs.freq.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/myo-yes.vs.myo-no_marker.freq_low.probs.freq.removed_sample.outliers.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/myo-yes.vs.myo-no_marker.freq_low.probs.freq.removed_sample.outliers.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/pbs-myo-yes.vs.pbs-myo-no_marker.freq_low.geno.freq.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/pbs-myo-yes.vs.pbs-myo-no_marker.freq_low.geno.freq.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/pbs-myo-yes.vs.pbs-myo-no_marker.freq_low.geno.freq.removed_sample.outliers.removed_geno.ratiov_4.batches_myo.csv
    Untracked:  data/pbs-myo-yes.vs.pbs-myo-no_marker.freq_low.geno.freq.removed_sample.outliers.removed_geno.ratiov_4.batches_myo_mis.csv
    Untracked:  data/pbs-myo-yes.vs.pbs-myo-no_marker.freq_low.probs.freq.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/pbs-myo-yes.vs.pbs-myo-no_marker.freq_low.probs.freq.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/pbs-myo-yes.vs.pbs-myo-no_marker.freq_low.probs.freq.removed_sample.outliers.removed_geno.ratio_4.batches_myo.csv
    Untracked:  data/pbs-myo-yes.vs.pbs-myo-no_marker.freq_low.probs.freq.removed_sample.outliers.removed_geno.ratio_4.batches_myo_mis.csv
    Untracked:  data/percent_missing_id_4.batches_myo.RData
    Untracked:  data/percent_missing_marker_4.batches_myo.RData
    Untracked:  data/pheno_4.batches_myo.csv
    Untracked:  data/physical_map_4.batches_myo.csv
    Untracked:  data/qc_info_bad_sample_4.batches_myo.RData
    Untracked:  data/sample_geno_AHB_4.batches_myo.csv
    Untracked:  data/sample_geno_bc_4.batches_myo.csv
    Untracked:  data/serreze_probs_4.batches_myo.rds
    Untracked:  data/serreze_probs_allqc_4.batches_myo.rds
    Untracked:  data/serreze_probs_allqc_4.batches_myo_mis.rds
    Untracked:  data/summary.cg_4.batches_myo.RData
    Untracked:  output/Percent_missing_genotype_data_4.batches_myo.pdf
    Untracked:  output/Percent_missing_genotype_data_per_marker_4.batches_myo.pdf
    Untracked:  output/Proportion_matching_genotypes_before_removal_of_bad_samples_4.batches_myo.pdf
    Untracked:  output/genotype_error_marker_4.batches_myo.pdf
    Untracked:  output/genotype_frequency_marker_4.batches_myo.pdf

Unstaged changes:
    Modified:   analysis/index_5.batches.Rmd

Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes.


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Genotype Summary by Sample

Neogen_Sample_ID Missing AA AC AG AT CC CG GC GG TA TC TG TT Total_Genotyped Percent_Genotyped MURGIGV01_SNP.Count cr
NM00185-ICI-Myo 5321 30457 1344 5697 9 31614 9 3 31761 2 5473 1348 30221 137938 96.29% 143259 0.962857481903406
D38-ICI-Myo 5346 29342 1811 7276 6 30520 6 4 30855 3 7190 1758 29142 137913 96.27% 143259 0.962682972797521
7927-ICI-Myo 5635 29819 1580 6562 8 30883 2 4 31138 3 6327 1566 29732 137624 96.07% 143259 0.960665647533488
D517-ICI-Myo 5197 28387 2202 9091 8 29402 5 5 29675 4 8944 2130 28209 138062 96.37% 143259 0.963723047068596
D1-PBS-Myo 5788 29470 1696 7014 7 30635 6 7 30856 1 6917 1689 29173 137471 95.96% 143259 0.959597651805471
D40-ICI-Myo 5330 29364 1789 7341 10 30473 5 3 30797 0 7342 1735 29070 137929 96.28% 143259 0.962794658625287
D251-PBS-Myo 5465 29931 1566 6519 7 30923 8 5 31165 1 6475 1571 29623 137794 96.19% 143259 0.961852309453507
D344-ICI-Myo 5362 30055 1556 6501 7 30944 8 4 31168 3 6330 1520 29801 137897 96.26% 143259 0.962571286969754
D90-ICI-EOI 5445 28203 2173 9129 7 29457 7 4 29735 3 8895 2061 28140 137814 96.20% 143259 0.961991916738215
6874-PBS-Myo 5336 29392 1818 7305 6 30462 7 4 30783 4 7126 1718 29298 137923 96.28% 143259 0.962752776439875
D351-ICI-Myo 21879 25617 1613 6385 4 27012 5 6 27387 2 6222 1581 25546 121380 84.73% 143259 0.847276610893556
7168-ICI-Myo 5555 31493 968 3897 6 32509 7 4 32790 0 3787 968 31275 137704 96.12% 143259 0.961224076672321

Gender Summary by Sample

Neogen_Sample_ID Provided.Sex Inferred.Sex
NM00185-ICI-Myo F F
D38-ICI-Myo F M
7927-ICI-Myo F F
D517-ICI-Myo F F
D1-PBS-Myo F F
D40-ICI-Myo F F
D251-PBS-Myo F F
D344-ICI-Myo F F
D90-ICI-EOI M M
6874-PBS-Myo F F
D351-ICI-Myo F M
7168-ICI-Myo F F

Phenotype Summary by Sample

Neogen_Sample_ID Myocarditis.Status age.of.clinical.phenotype..weeks. clinical.pheno Drug.Treatment
NM00185-ICI-Myo YES 13.1 SICK ICI
D38-ICI-Myo YES 17.9 SICK ICI
7927-ICI-Myo YES 13.3 SICK ICI
D517-ICI-Myo YES 13 SICK ICI
D1-PBS-Myo YES 38.3 SICK PBS
D40-ICI-Myo YES 12.9 SICK ICI
D251-PBS-Myo YES 12.3 SICK PBS
D344-ICI-Myo YES 13 SICK ICI
D90-ICI-EOI NO EOI ICI
6874-PBS-Myo YES 21.1 SICK PBS
D351-ICI-Myo YES 13 SICK ICI
7168-ICI-Myo YES 13.3 SICK ICI

All Problematic Samples

Neogen_Sample_ID no_pheno low_call.rate different_sex
2 D38-ICI-Myo XX
11 D351-ICI-Myo XX XX

R version 4.2.2 (2022-10-31)
Platform: x86_64-apple-darwin17.0 (64-bit)
Running under: macOS Big Sur ... 10.16

Matrix products: default
BLAS:   /Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libRblas.0.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libRlapack.dylib

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] tibble_3.1.8      readxl_1.4.1      cluster_2.1.4     dplyr_1.0.10     
 [5] optparse_1.7.3    rhdf5_2.40.0      mclust_6.0.0      tidyr_1.2.1      
 [9] data.table_1.14.6 knitr_1.41        kableExtra_1.3.4  workflowr_1.7.0  

loaded via a namespace (and not attached):
 [1] tidyselect_1.2.0   xfun_0.35          bslib_0.4.1        purrr_0.3.5       
 [5] colorspace_2.0-3   vctrs_0.5.1        generics_0.1.3     getopt_1.20.3     
 [9] htmltools_0.5.3    viridisLite_0.4.1  yaml_2.3.6         utf8_1.2.2        
[13] rlang_1.0.6        jquerylib_0.1.4    later_1.3.0        pillar_1.8.1      
[17] withr_2.5.0        DBI_1.1.3          glue_1.6.2         lifecycle_1.0.3   
[21] stringr_1.5.0      cellranger_1.1.0   munsell_0.5.0      rvest_1.0.3       
[25] evaluate_0.18      callr_3.7.3        fastmap_1.1.0      httpuv_1.6.6      
[29] ps_1.7.2           fansi_1.0.3        Rcpp_1.0.9         promises_1.2.0.1  
[33] scales_1.2.1       cachem_1.0.6       webshot_0.5.4      jsonlite_1.8.4    
[37] fs_1.5.2           systemfonts_1.0.4  digest_0.6.30      stringi_1.7.8     
[41] processx_3.8.0     getPass_0.2-2      rprojroot_2.0.3    rhdf5filters_1.8.0
[45] cli_3.4.1          tools_4.2.2        magrittr_2.0.3     sass_0.4.4        
[49] whisker_0.4.1      pkgconfig_2.0.3    ellipsis_0.3.2     xml2_1.3.3        
[53] assertthat_0.2.1   rmarkdown_2.18     svglite_2.1.0      httr_1.4.4        
[57] rstudioapi_0.14    Rhdf5lib_1.18.2    R6_2.5.1           git2r_0.30.1      
[61] compiler_4.2.2