Last updated: 2023-04-13

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Knit directory: Serreze-T1D_Workflow/

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Genotype Summary by Sample

Neogen_Sample_ID Missing AA AC AG AT CC CG GC GG TA TC TG TT Total_Genotyped Percent_Genotyped MURGIGV01_SNP.Count cr
D265-PBS-EOI 5314 29410 1839 7396 10 30351 12 10 30656 4 7205 1735 29317 137945 96.29% 143259 0.962906344453054
D434-PBS-Myo 5368 30678 1306 5457 7 31584 4 1 31834 2 5340 1290 30388 137891 96.25% 143259 0.962529404784342
D1465-PBS-Myo 5283 30288 1504 6072 4 31069 4 4 31435 5 6090 1429 30072 137976 96.31% 143259 0.963122735744351
D270-PBS-Myo 5266 29081 1920 8144 9 30002 5 2 30145 2 7870 1927 28886 137993 96.32% 143259 0.963241401936353
D439-PBS-Myo 5311 30592 1334 5573 2 31564 4 3 31777 0 5317 1360 30422 137948 96.29% 143259 0.96292728554576
D1485-ICI-Myo 5311 29607 1732 7167 7 30457 6 3 30767 4 7011 1707 29480 137948 96.29% 143259 0.96292728554576
D306-ICI-EOI 5231 29134 1898 7975 6 30093 6 4 30288 1 7810 1886 28927 138028 96.35% 143259 0.963485714684592
D441-PBS-Myo 5190 30097 1478 6418 5 31131 4 1 31329 0 6146 1498 29962 138069 96.38% 143259 0.963771909618244
D1500-ICI-Myo 5820 28684 2108 8699 8 29339 7 7 29549 4 8442 2038 28554 137439 95.94% 143259 0.959374280149938
D314-ICI-Myo 5546 28729 2164 8551 10 29509 10 7 29717 3 8415 2034 28564 137713 96.13% 143259 0.961286899950439
D447-PBS-Myo 5589 29873 1694 6683 4 30467 3 6 30914 3 6718 1666 29639 137670 96.10% 143259 0.960986744288317
D1521-ICI-Myo 5182 29579 1746 7254 10 30559 6 3 30785 0 7028 1676 29431 138077 96.38% 143259 0.963827752532127
D316-ICI-Myo 5221 30026 1647 6491 4 30827 2 4 31207 5 6401 1540 29884 138038 96.36% 143259 0.963555518326946
D475-PBS-Myo 5207 28756 2069 8360 12 29780 6 5 30124 4 8237 2026 28673 138052 96.37% 143259 0.963653243426242
D1584-ICI-Myo 5385 29644 1694 6998 4 30556 2 4 30859 1 6965 1719 29428 137874 96.24% 143259 0.96241073859234
D323-PBS-Myo 5165 28426 2243 9078 8 29335 7 9 29625 5 8889 2196 28273 138094 96.39% 143259 0.963946418724129
D522-PBS-Myo 5803 29582 1817 7236 9 30234 7 5 30456 4 7003 1708 29395 137456 95.95% 143259 0.95949294634194
D1593-ICI-Myo 5826 30153 1460 6170 9 30938 6 4 31219 5 6064 1480 29925 137433 95.93% 143259 0.959332397964526
D324-PBS-Myo 5212 29171 1952 7972 7 30007 7 6 30259 3 7858 1886 28919 138047 96.36% 143259 0.963618341605065
D530-ICI-Myo 5210 30270 1525 6140 5 31034 5 3 31401 3 6099 1523 30041 138049 96.36% 143259 0.963632302333536
7275-PBS-SICK 5295 30355 1477 5876 4 31223 7 4 31567 3 5842 1467 30139 137964 96.30% 143259 0.963038971373526
D331-PBS-Myo 5285 29947 1641 6617 8 30903 8 5 31103 3 6403 1616 29720 137974 96.31% 143259 0.96310877501588
D805-ICI-Myo 5218 29477 1817 7321 7 30346 2 1 30710 2 7297 1793 29268 138041 96.36% 143259 0.963576459419653
7798-PBS-SICK 5148 28708 2136 8787 10 29626 7 4 29777 4 8381 2043 28628 138111 96.41% 143259 0.964065084916131
D341-PBS-Myo 5573 28946 1980 8159 6 29773 7 5 30063 0 8039 1958 28750 137686 96.11% 143259 0.961098430116083
D1167-PBS-Myo 5330 30248 1469 6042 5 31284 4 2 31495 0 5867 1467 30046 137929 96.28% 143259 0.962794658625287
8617-PBS-SICK 5214 29419 1842 7376 7 30386 5 5 30705 5 7268 1766 29261 138045 96.36% 143259 0.963604380876594
D354-ICI-Myo 5250 29237 1995 7720 6 30053 8 6 30432 3 7628 1833 29088 138009 96.34% 143259 0.96335308776412
D1320-ICI-Myo 5310 30178 1480 6197 10 31109 6 5 31378 2 6184 1499 29901 137949 96.29% 143259 0.962934265909995
D244-PBS-SICK 5272 29435 1805 7393 8 30444 8 6 30688 3 7137 1746 29314 137987 96.32% 143259 0.963199519750941
D365-ICI-Myo 5202 29597 1757 7181 9 30519 8 8 30880 3 6957 1611 29527 138057 96.37% 143259 0.963688145247419
D1368-ICI-Myo 5180 29537 1809 7461 9 30387 7 4 30563 1 7371 1745 29185 138079 96.38% 143259 0.963841713260598
D252-PBS-Myo 5284 30527 1384 5638 6 31448 2 7 31774 3 5537 1358 30291 137975 96.31% 143259 0.963115755380116
D423-PBS-Myo 5280 30308 1496 5978 7 31186 7 6 31513 3 5877 1472 30126 137979 96.31% 143259 0.963143676837057
D1400-ICI-Myo 5186 29701 1724 6974 6 30601 3 4 30965 2 6918 1662 29513 138073 96.38% 143259 0.963799831075186
D253-PBS-SICK 5229 30498 1448 5790 5 31325 7 5 31635 3 5718 1376 30220 138030 96.35% 143259 0.963499675413063

Gender Summary by Sample

Neogen_Sample_ID Provided.Sex Inferred.Sex
D265-PBS-EOI F F
D434-PBS-Myo F F
D1465-PBS-Myo F F
D270-PBS-Myo F F
D439-PBS-Myo F F
D1485-ICI-Myo F F
D306-ICI-EOI F F
D441-PBS-Myo F F
D1500-ICI-Myo F F
D314-ICI-Myo F F
D447-PBS-Myo F F
D1521-ICI-Myo F F
D316-ICI-Myo F F
D475-PBS-Myo F F
D1584-ICI-Myo F F
D323-PBS-Myo F F
D522-PBS-Myo F F
D1593-ICI-Myo F F
D324-PBS-Myo F F
D530-ICI-Myo F F
7275-PBS-SICK F F
D331-PBS-Myo F F
D805-ICI-Myo F F
7798-PBS-SICK F F
D341-PBS-Myo F F
D1167-PBS-Myo F F
8617-PBS-SICK F F
D354-ICI-Myo F F
D1320-ICI-Myo F F
D244-PBS-SICK F F
D365-ICI-Myo F F
D1368-ICI-Myo F F
D252-PBS-Myo F F
D423-PBS-Myo F F
D1400-ICI-Myo F F
D253-PBS-SICK F F

Phenotype Summary by Sample

Neogen_Sample_ID sex_pheno Inferred.Sex_pheno Myocarditis.Status age.of.clinical.phenotype..weeks.
D265-PBS-EOI F F NO
D434-PBS-Myo F F YES
D1465-PBS-Myo F F YES 16.1
D270-PBS-Myo F F YES
D439-PBS-Myo F F YES
D1485-ICI-Myo F F YES 13
D306-ICI-EOI F F NO
D441-PBS-Myo F F YES
D1500-ICI-Myo F F YES 13.5
D314-ICI-Myo F F YES
D447-PBS-Myo F F YES
D1521-ICI-Myo F F YES 13
D316-ICI-Myo F F YES
D475-PBS-Myo F F YES 37.1
D1584-ICI-Myo F F YES 13
D323-PBS-Myo F F YES
D522-PBS-Myo F F YES 36.1
D1593-ICI-Myo F F YES 13.4
D324-PBS-Myo F F YES 38.1
D530-ICI-Myo F F YES 35.1
7275-PBS-SICK F F NO
D331-PBS-Myo F F YES
D805-ICI-Myo F F YES 27
7798-PBS-SICK F F NO
D341-PBS-Myo F F YES
D1167-PBS-Myo F F YES 23.4
8617-PBS-SICK F F NO
D354-ICI-Myo F F YES
D1320-ICI-Myo F F YES 13.2
D244-PBS-SICK F F NO
D365-ICI-Myo F F YES
D1368-ICI-Myo F F YES 31
D252-PBS-Myo F F YES 36.7
D423-PBS-Myo F F YES
D1400-ICI-Myo F F YES 13
D253-PBS-SICK F F NO

All Problematic Samples

Neogen_Sample_ID no_pheno low_call.rate different_sex

R version 4.2.2 (2022-10-31)
Platform: x86_64-apple-darwin17.0 (64-bit)
Running under: macOS Big Sur ... 10.16

Matrix products: default
BLAS:   /Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libRblas.0.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libRlapack.dylib

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] tibble_3.1.8      readxl_1.4.1      cluster_2.1.4     dplyr_1.0.10     
 [5] optparse_1.7.3    rhdf5_2.40.0      mclust_6.0.0      tidyr_1.2.1      
 [9] data.table_1.14.6 knitr_1.41        kableExtra_1.3.4  workflowr_1.7.0  

loaded via a namespace (and not attached):
 [1] tidyselect_1.2.0   xfun_0.35          bslib_0.4.1        purrr_0.3.5       
 [5] colorspace_2.0-3   vctrs_0.5.1        generics_0.1.3     getopt_1.20.3     
 [9] htmltools_0.5.3    viridisLite_0.4.1  yaml_2.3.6         utf8_1.2.2        
[13] rlang_1.0.6        jquerylib_0.1.4    later_1.3.0        pillar_1.8.1      
[17] withr_2.5.0        DBI_1.1.3          glue_1.6.2         lifecycle_1.0.3   
[21] stringr_1.5.0      cellranger_1.1.0   munsell_0.5.0      rvest_1.0.3       
[25] evaluate_0.18      callr_3.7.3        fastmap_1.1.0      httpuv_1.6.6      
[29] ps_1.7.2           fansi_1.0.3        Rcpp_1.0.9         promises_1.2.0.1  
[33] scales_1.2.1       cachem_1.0.6       webshot_0.5.4      jsonlite_1.8.4    
[37] fs_1.5.2           systemfonts_1.0.4  digest_0.6.30      stringi_1.7.8     
[41] processx_3.8.0     getPass_0.2-2      rprojroot_2.0.3    rhdf5filters_1.8.0
[45] cli_3.4.1          tools_4.2.2        magrittr_2.0.3     sass_0.4.4        
[49] whisker_0.4.1      pkgconfig_2.0.3    ellipsis_0.3.2     xml2_1.3.3        
[53] assertthat_0.2.1   rmarkdown_2.18     svglite_2.1.0      httr_1.4.4        
[57] rstudioapi_0.14    Rhdf5lib_1.18.2    R6_2.5.1           git2r_0.30.1      
[61] compiler_4.2.2