Class AnalysisOptions.Builder
java.lang.Object
org.monarchinitiative.lirical.core.analysis.AnalysisOptions.Builder
- Enclosing interface:
- AnalysisOptions
A builder for
AnalysisOptions
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Method Summary
Modifier and TypeMethodDescriptionaddDiseaseDatabases
(Collection<org.monarchinitiative.phenol.annotations.io.hpo.DiseaseDatabase> diseaseDatabases) addDiseaseDatabases
(org.monarchinitiative.phenol.annotations.io.hpo.DiseaseDatabase... diseaseDatabases) build()
defaultVariantBackgroundFrequency
(double defaultVariantBackgroundFrequency) genomeBuild
(GenomeBuild genomeBuild) includeDiseasesWithNoDeleteriousVariants
(boolean includeDiseasesWithNoDeleteriousVariants) pretestProbability
(PretestDiseaseProbability pretestDiseaseProbability) setDiseaseDatabases
(Collection<org.monarchinitiative.phenol.annotations.io.hpo.DiseaseDatabase> diseaseDatabases) transcriptDatabase
(TranscriptDatabase transcriptDatabase) useGlobal
(boolean useGlobal) useStrictPenalties
(boolean useStrictPenalties) variantDeleteriousnessThreshold
(float variantDeleteriousnessThreshold)
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Method Details
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genomeBuild
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transcriptDatabase
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clearDiseaseDatabases
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addDiseaseDatabases
public AnalysisOptions.Builder addDiseaseDatabases(org.monarchinitiative.phenol.annotations.io.hpo.DiseaseDatabase... diseaseDatabases) -
addDiseaseDatabases
public AnalysisOptions.Builder addDiseaseDatabases(Collection<org.monarchinitiative.phenol.annotations.io.hpo.DiseaseDatabase> diseaseDatabases) -
setDiseaseDatabases
public AnalysisOptions.Builder setDiseaseDatabases(Collection<org.monarchinitiative.phenol.annotations.io.hpo.DiseaseDatabase> diseaseDatabases) -
variantDeleteriousnessThreshold
public AnalysisOptions.Builder variantDeleteriousnessThreshold(float variantDeleteriousnessThreshold) -
defaultVariantBackgroundFrequency
public AnalysisOptions.Builder defaultVariantBackgroundFrequency(double defaultVariantBackgroundFrequency) -
useStrictPenalties
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useGlobal
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pretestProbability
public AnalysisOptions.Builder pretestProbability(PretestDiseaseProbability pretestDiseaseProbability) -
includeDiseasesWithNoDeleteriousVariants
public AnalysisOptions.Builder includeDiseasesWithNoDeleteriousVariants(boolean includeDiseasesWithNoDeleteriousVariants) -
build
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